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Xylometazoline HCl


General information

Xylometazoline is a direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds. Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (╬▒)-adrenergic receptors to cause vasoconstriction of nasal blood vessels.

Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies.

Trade names

Otrivin, Sinutab, Nasoferm, Nasic

About the API

Therapeutic areas



USP, Ph. Eur.

Regulatory documentation


Production location


Standard pack size

1kg, 5kg, 10kg

Physical properties

Crystalline substance

Typical formulation types

Nasal topical

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