As your flexible partner, Siegfried provides reliable and consistent commercial supply combined with high quality product and performance. We provide versatile cGMP manufacturing capability and robust manufacturing processes that meet your unique market needs.
Siegfried maintains GMP-certified and FDA-audited manufacturing plants for contract manufacturing of oral solids such as granulates, tablets, film tablets and hard capsules filled with powder, granules or pellets.
Small batches are produced in our plant in Zofingen (Switzerland), ideal for orphan drugs or niche products, whereas annual volumes are low. Commercial manufacturing takes place at our production facility in Hal Far (Malta, EU).
Both locations have a multitude of state of the art technologies to manufacture various solid oral dosage forms, including:
- Power blending
- High shear mixer
- Fluid bed systems with top and bottom spray (Wurster)
- Roller Compaction
- Tablet presses with bi/trilayer capability
- Perforated drum film coater
- Hard Shell Capsule lines for powder, granules, pellets and minitablets filling
- Blister lines for thermoform and cold form blister packaging, including Aluminium/Aluminium
We can handle a broad range of batch sizes (0.5kg - 350kg). Our equipment types are selected to match and harmonize with one another, ensuring simple scale-up in case of increasing demand.
Both manufacturing plants have an additional, segregated area to process highly-active and low-dose substances (OEL 1-10 µg/m³) to pharmaceutical dosage forms.
For more information about our manufacturing facilities and their corresponding equipment, please contact Business Development. Whatever your production requirements may be, you can expect more from Siegfried.
Steriles & Biologics
Siegfried offers specialized contract aseptic manufacturing and analytical services for both the pharmaceutical and biotechnology industries. Siegfried Irvine (USA) and Siegfried Hameln (Germany) have know-how and extensive expertise to support small and large scale productions.
Injectable and ophtalmic products are manufactured at Siegfried's Irvine state-of-the-art facility with small scale through commercial batch scale manufacturing capability with 1L-2000L.
With Siegfried's Hameln state-of-the-art facility in Germany, we provide our customers with more capabilities and capacity in the critical field of the parenterals manufacturing, visual inspection and packaging. Our award-winning new facility can produce sterile liquid vials and ampoules, manufactured under aseptic conditions on eight automated RABs protected filling lines, to terminally sterilize them, if needed.
Siegfried supports the value chain for aseptic services from simple to complex formulation exceeding your expectations with unsurpassed service and quality.
Our main capabilities are:
- Aseptic Filling:
- Biologics and Chemical
- Container Closures:
- Dropper Tip Bottles
- Squeeze tubes
- Screw Cap Bottles
- Pre-Filled Syringes (PFS)
- Combination / Drug Delivery Devices:
- Drug Coated Implants
- Drug Delivery Devices
- Sustained Release Delivery Systems
Whatever your sterile production requirements might be, please contact Siegfried. We will be delighted to exceed your expectations.