Chemistry Capabilities

Siegfried has vast experience with reactions from the following classes including scale-up of those reactions to commercial quantities:

C-C Bonds Aldol reactions (Knoevenagel condensation, Dieckmann, etc.)
Baylis-Hillman reaction
Blanc chloromethylation
Cyanation (NaCN, KCN)
Diels-Alder reaction
Fries rearrangement
Favorskii reaction
(Mizoroki-)Heck reaction
Grignard reaction
Mannich reaction
Michael reaction
Suzuki reaction
Wittig reaction
C-Heteroatom Bond Forming Reactions Alkylations
Azide chemistry (NaN3)
Buchwald-Hartwig amination
Mannich reaction
Leuckart reaction
Reductive amination
Ritter reaction
Williamson reaction
Chiral Resolutions Enzyme-catalyzed kinetic resolutions of racemic esters
Resolution by formation of diastereomeric salts
Chiral Catalysis Enzymatic saponification
Chiral reduction
Sharpless dihydroxylation (Bishydroxylation)
Metal-organic Reactions Boronic acids
Cyro reactions down up to -100°C
Grignard reaction
Lithium-Halogen exchange
Ortho-Lithiation
Reformatsky reaction
Organozinc reaction
Homogenous Catalysis by Noble Metals Asymmetric hydrations
Buchwald-Hartwig amination
Carbonylation of haloaromatics (CO insertion)
Heck reaction
Sharpless dihydroxylation (bishydroxylation)
Suzuki reaction
Aromatic Ring Substitutions Bromintion
Chlorination
Chlorosulfonation
Diazo coupling
Friedel-Crafts acylations
Friedel-Crafts alkylations
Gattermann aldehyde synthesis
Nitration
Vilsmeier-Haack reaction
Functional Group Transformation  Alcoholysis
Aminolysis
Amidation
Bechamp reduction
Beckmann rearrangement
Finkelstein reaction
Hofmann rearrangement
N-Demethylations (from Braun reaction, etc.)
O-Demethylations
Oxidation with O2
Oxidation with KMnO4
Ritter reaction
Sandmeyer reaction
Esterification
Reductions and Oxidations Alkene reductions
Bechamp reduction
Chiral reductions
Heterogenous catalysis
Homogenous catalysis
Meerwein-Ponndorf-Verley (MPV) reduction
Oxidation of non-substituted C-structures
Oxidation with O2
Oxidation with KMnO4
Reductive amination
Reduction of nitro groups
Swern oxidation
Wolff-Kishner reduction
Cyclizations Azide chemistry (NaN3)
Heteroatom cyclizations
Diels-Alder reaction
Fischer indole synthesis
Hantzsch pyrrole synthesis
Hantzsch pyridine synthesis
Knorr pyrrole synthesis
Protecting Group Chemistry  Acetal
Benzyl
BOC
CBZ
Silyl ethers (TMS, TBDMS, ..)
Reactions with Special Chemicals Azide chemistry (NaN3)
Borane
Cyanation (NaCN, KCN)
Cyanogen bromide
Dimethyl sulfate
Epichlorohydrin
Halogens (chlorine, bromine, iodine)
Oxidation with KMnO4
Phosgene, triphosgene

Looking for something else? We can make it happen!

We would be pleased to answer all your questions regarding these and other types of reactions. 

Expect more with Siegfried as your preferred Service Partner

to the top to top

Can't find the information
you are looking for?
Contact us

Siegfried AG
Untere Bruehlstrasse 4
CH-4800 Zofingen

Phone: +41 62 746 1111
Fax: +41 62 746 1202
info@siegfried.ch